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PRODUCTS |
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β-Glucosidase Chemiluminescent Substrates |
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| Available Sizes |
100mg |
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500mg |
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1.0g |
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2.0g to 10.0g |
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Application |
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| Sβ-Glu101 |
beta-D-glucosidase Substrate in Buffer |
beta-Glucosidase enzyme, Reporter gene assays |
| Sβ-Glu102 |
beta-D-glucosidase Substrate in Buffer Plus |
beta-Glucosidase enzyme, Reporter gene assays |
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Chemiluminescent Substrate for β-Glucosidase Enzyme |
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| ß-Glucosidase Enzyme is present in nearly all species. It is reported that people with Gaucher’s disease have ß-Glucosidase gene mutations, which results in abnormal lysosomal storage. |
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| Our new series of ultra-sensitive 1, 2-dioxetanes can detect ß- Glucosidase enzyme at very low level. MDLLC chemiluminescent system is at least 1000 times more sensitive compared to the chromophoric substrates. These novel 1, 2-dioxetanes are protected by US Patent 6,461,876B1and other pending PCT and US patent applications. |
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| MDLLC substrates for ß-Glucosidase enzyme are more sensitive due to the effect of p-electrons on the decomposition of 1, 2-dioxetanes intermediate in the form of phenoxide ion formed after the interaction of glucoside group on 1, 2-dioxetane and ß-Glucosidase enzyme and can be shown as: |
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