PRODUCTS
     
     
    β-Glucosidase Chemiluminescent Substrates
     
   
Available Sizes 100mg
  500mg
  1.0g
  2.0g to 10.0g
   
    Application
Sβ-Glu101 beta-D-glucosidase Substrate in Buffer beta-Glucosidase enzyme, Reporter gene assays
Sβ-Glu102 beta-D-glucosidase Substrate in Buffer Plus beta-Glucosidase enzyme, Reporter gene assays
     
     
    Chemiluminescent Substrate for β-Glucosidase Enzyme
   
ß-Glucosidase Enzyme is present in nearly all species. It is reported that people with Gaucher’s disease have ß-Glucosidase gene mutations, which results in abnormal lysosomal storage.
 
Our new series of ultra-sensitive 1, 2-dioxetanes can detect ß- Glucosidase enzyme at very low level. MDLLC chemiluminescent system is at least 1000 times more sensitive compared to the chromophoric substrates. These novel 1, 2-dioxetanes are protected by US Patent 6,461,876B1and other pending PCT and US patent applications.
 
MDLLC substrates for ß-Glucosidase enzyme are more sensitive due to the effect of p-electrons on the decomposition of 1, 2-dioxetanes intermediate in the form of phenoxide ion formed after the interaction of glucoside group on 1, 2-dioxetane and ß-Glucosidase enzyme and can be shown as: